Biotechnology

The German-Polish Double-Degree Program is the only internationally cooperative Master's program in biotechnology in the state of Baden-Württemberg.
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M+V Department

Modulhandbook

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Biotechnological Processes from Lab to Market

Prerequisite

Fundamentals of biotechnology and process engineering
Teaching methods Lecture/Lab
Learning target / Competences

Students are equipped with comprehensive understanding of all process steps relating to bioproducts of industrial importance.

They are able to define and assess the procedures for biomanufacturing. They know how to select the appropriate process steps and how to evaluate process alternatives.

 

 

 
Duration 1
Hours per week 8.0
Overview
Classes 120
Individual / Group work: 180
Workload 300
ECTS 10.0
Requirements for awarding credit points

written examination, 90 minutes, and laboratory report(s)

The module grade is composed of the exam grade (50%) and the laboratory grade (50%).
Credits and grades

 

 

 
Responsible person

Professor Dr. rer. nat. Thomas Eisele
Recommended semester 1
Frequency Annually (ws)
Usability

Master MBT
Lectures

Biotechnological Processes from Lab to Market

Type Lecture
Nr. M+V2500
Hours per week 4.0
Content

The students will aquire knowledge in the preparation of business cases and the finacial evaluation of biotechnological projects. Moreover, an introduction in the protection of intellectual property will be given. 

In a case study, students will aquire knowledge how to develop industrial products starting with bioinformatics via the recombinant expression of proteins in Pichia pastoris. The purification of proteins as well as the characterization of enzymes will be covered in depth. Bioanalytical knowledge is acquired in the field of Circular Economy. In detail, methods for bioanalytics are discussed (HPTLC, HPLC, GC and IC). Finally, knowledge is imparted in the area of upstream and downstream processing. This includes, for example, the production of cellulases in Trichoderma reesei.

 
Literature
  • Doran, P.M.: Bioprocess Engineering principles, second edition, Elsevier 2013
  • Villadssen, J.; Liden, G.; Nielsen, J.: Bioreaction Engineering Principles, Springer 2011
  • Dunn, I.J.; Heinzle, E.; Ingham, J.; Prenosil, J.E.: Biological Reaction Engineering, Wiley-VCH, 2003
  • Dutta, R.: Fundamentals of Biochemical Engineering. Springer 2008
  • Chmiel, H.: Bioprozesstechnik, Elsevier Spektrum Akademischer Verlag, 2006

Biotechnological Processes from Lab to Market - Lab

Type Lab
Nr. M+V2501
Hours per week 4.0
Content

The students will conduct several full day experiments:

  1. Buffer preparation, dilutions and protein quantification
  2. Enzyme Purification using Fast Protein Liquid Chromatography as well a SDS-PAGE
  3. Enzyme kinetic using the previously purified Enzymes
  4. Optinally: Bioreactor fermentation in 5 - 10 L scale
Literature

Script Lab to Market: Biotechnological Processes from Lab to Market
 
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